Inorganic Chemistry, porphyrin catalysis and metalloporphyrins. Over thirty years of research at UFPR, post-doctoral work at UIUC, collaborations across four continents. Current member of the CNPq-QU Advisory Committee. Member for over 35 years and former President of the Brazilian Chemical Society. Founding member of the Society of Porphyrins and Phthalocyanines (SPP).
Shirley Nakagaki is a Full Professor at the Department of Chemistry of the Federal University of Paraná (UFPR), where she has been based since 1992. She earned her degree in Chemistry from USP Ribeirão Preto, her Master's and PhD from UNESP Araraquara, and conducted postdoctoral research at the University of Illinois at Urbana-Champaign under Professor Kenneth S. Suslick.
Her research focuses on the synthesis, characterization, and application of metalloporphyrins — molecules that mimic the action of natural enzymes to accelerate oxidation, esterification, and transesterification reactions, among others. Applications range from cleaner fuels to sustainable industrial processes.
"I will make sure I will not be the last." — on becoming only the second woman to lead the Brazilian Chemical Society in its 45-year history.
She is a CNPq Research Fellow (Level 1B) and a full member of the RSC Advances Editorial Board, a leading journal of the Royal Society of Chemistry (UK). She is a founding member of the Society of Porphyrins and Phthalocyanines (SPP) and Brazil's representative in that international society. She maintains active research collaborations with groups in France, Portugal, Spain, Japan, the United States, Australia, and the United Kingdom.
Porphyrins are molecules with a distinctive geometry: four nitrogen-containing rings arranged around a central metal atom. In nature, hemoglobin and chlorophyll are porphyrins; in Prof. Shirley's laboratory, they become powerful catalysts.
Her research focuses on developing compounds that mimic enzymes like cytochrome P-450 to promote selective oxidation reactions. These systems have key applications in Green Chemistry, biodiesel production, and the synthesis of high-value compounds.
Immobilization of metalloporphyrinic catalysts on inorganic supports for selective oxidation reactions applicable to clean industrial processes.
Catalytic systems that mimic cytochrome P-450 — the enzyme responsible for drug metabolism and xenobiotic transformation in living organisms.
Development of solid catalysts for esterification and transesterification reactions, targeting sustainable biodiesel production and new biofuels.
Synthesis and modification of microporous and mesoporous solids (silicas and clays) derived from porphyrins for catalytic applications and gas storage.
One-pot systems capable of carrying out multiple chemical transformations in a single step, reducing waste and improving process efficiency.
Active partnerships with groups in France, Japan, USA, and Europe. Extensive scientific output with international co-authorship and leadership in global societies.
LABIOINC is one of the most active research groups in Brazil in the area of metalloporphyrins, based at the Department of Chemistry of the Federal University of Paraná. Over more than three decades, the laboratory has trained dozens of researchers now working at universities, research institutes, and industries in Brazil and abroad.
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Federal University of Paraná, Exact Sciences Sector, Department of Chemistry.